As one of the leading medicinal chemistry companies, offering clients a huge amount of chemistry experience and technical expertise, our lead optimisation (medicinal chemistry) services focus on the delivery of key target compounds. With a very high success rate and an established record of accomplishment, this really is our bread-and-butter.
Our medicinal chemistry service expertise in route design and parallel synthesis of small focused library sets (typically 5 to 50 compounds) ensures your leads are efficiently optimised.
Our in-house custom synthesis capability and state-of-the-art equipment allows us to quickly and cost effectively synthesise, optimise and progress leads to the next stage of development.
We have over 25 PHD-qualified full-time equivalents (FTEs) who can support you on your projects. Whether this takes a few months or over a year, our experts are here to make sure you can achieve project success.
Typical lead optimisation (medicinal chemistry) services include:
- Route scouting/design followed by first known synthesis
- Custom synthesis of analogues of lead and second generation compounds
- Custom synthesis of focused library sets (5-50 compounds, 5-250 mg, >95% purity)
- Rapid scale-up of high priority compounds
We provide a value added lead optimisation (medicinal chemistry) service with an emphasis on compound quality, purity and pharmacological properties. We pride ourselves on being one of the top UK medicinal chemistry companies and strive to offer the highest quality of service. This means supporting our chemists so they can innovate and work on your programs more effectively. If required, we also have additional lead optimisation support from our Baroda site in India.