Onyx Scientific offers specialist solid state services that are integrated with our other chemistry services and focused on cutting lead times and ensuring processes are scalable. Our solid state services can be carried out in parallel with process development or after depending on your project’s needs.

Given that a high percentage of all drugs are formulated in solid dosage form, the need to understand, control and characterise the individual forms of a drug substance, particular the polymorphic form, is vital. Each polymorph displays unique physicochemical properties that can affect bioavailability, manufacturability, stability and other performance characteristics of the drug.

Our solid state services are designed to gather information about your drug substance to give your project the best chance of success.

For example, appropriate polymorphic form selection with desirable properties (e.g. for filtration) can be of huge benefit to process efficiency and/or purity and plays an important part in intellectual property (IP) strategy throughout a drug’s lifecycle.

If you’d like to know more about our solid state services and solid state chemistry capabilities or any of our contract research and manufacturing services, then please get in touch today.