We offer specialist solid state services that are integrated with our other chemistry services. This service is also focused on cutting lead times and ensuring processes are scalable and efficient. Our solid state services can be carried out in parallel with process development and often aid purification issues.
Because a high percentage of all drugs are formulated in a solid dosage form, the need to understand, control and characterise the individual forms of a drug substance, particularly the polymorphic form, is vital. Each polymorph displays unique physicochemical properties that can affect bioavailability, manufacturability, stability and other performance characteristics.
Our solid state services are designed to gather information about your drug substance to give your project the best chance of success. For example, appropriate polymorphic form selection with desirable properties (e.g. for filtration) can be of huge benefit to process efficiency and purity. This also plays an important part in the intellectual property (IP) strategy throughout a drug’s lifecycle.
If you’d like to know more about our solid state services, please get in touch today.