We were recommended to Onyx Scientific by an industry contact, who had been very impressed with how the team had operated. The team were able to take our project on at short notice and support us right away without any fuss. We have found the team to be responsive, competent and straightforward to deal with, which has been invaluable to our project.
Onyx Scientific has a niche in the market. As a contract manufacturing organisation that doesn’t have to bear the high costs of running a pilot plant, it can deliver high quality materials for IND-enabling toxicology studies and early phase development in a cost-effective manner. We would definitely recommend Onyx for anyone considering their options for scale-up and GMP synthesis.
We have found Onyx Scientific to be a cost-effective CMO for API scale-up as well as related analytical and solid-state development related to ESN364, Euroscreen’s clinical candidate currently in clinical trials. In fact, we found Onyx Scientific to be cost competitive even when compared against certain Indian CMOs. In addition to this, Onyx Scientific offers the added advantage of proximity in terms of location (and time zone), ease of communication as well as their experience and know-how.
AstraZeneca has worked with Onyx Scientific for many years for early-phase process development and the supply of drug substances. This is clearly an area of expertise for Onyx Scientific and we continue to be impressed by their excellent technical capability, combined with their strong customer focus and collaborative approach. These qualities mean that Onyx Scientific routinely meet or exceed our project requirements.
As we have moved towards advancing our clinical trial schedule, we have been very pleased with the continued commitment, expertise and support that Onyx Scientific has provided. The team’s flexibility and attention to detail throughout the process, including the adherence to stringent cleaning validation procedures, has assisted us in keeping our project on-track.
We were delighted with the service provided by Onyx Scientific in conjunction with Reach Separations in carrying out full characterisation and identification. The joint effort allowed us to undertake impurity synthesis to get a positive identification of impurity followed by the purification of a sample by prep LC. We found the whole process to be quick, efficient and cost-effective.
Importantly, when working with Onyx Scientific, our project was delivered on time and within budget. The team at Onyx communicated well and we were pleased with the quality of the final product.
We have worked with Onyx Scientific for a number of years and have been very impressed by the team's excellent flexibility and responsiveness throughout. They have demonstrated strong technical capability in carrying out PR&D scale-up and GMP manufacture on multiple Phase I projects. By utilising their solid state offering alongside the PR&D work, this ensured a very efficient programme with respect to salt selection. Vitally for us, their team has supported our application process through fast turnaround.
Onyx Scientific has proven to be technically very capable when it comes to carrying out analytical projects. The team took their time to understand our specific requirements and came up with solutions to overcome any challenges. Communication with the team has been particularly excellent. Importantly for us, the speed of delivery was also exceptional.
We were very impressed with the speed at which the team at Onyx Scientific initially responded to our enquiry. We required our compound within six weeks and were delighted to take delivery of our material well within this very tight timescale. Onyx Scientific’s team were friendly and knowledgeable. In addition to this, the facilities, equipment and reports were first-class and the project on the whole ran incredibly smoothly.
Onyx Scientific provided an excellent service, responding very quickly to our needs with the flexibility that the nature of our work requires. They have coped easily with the higher volume of work and the data we are getting is as good as we could ask for. The Onyx Scientific team continues to go beyond the call of duty and will enable us to make great progress going forwards. An outstanding experience all around.
Cyclacel has worked closely with Onyx Scientific for a number of years. The team has provided synthetic chemistry and analytical expertise for our late stage research programmes and early development projects, such that we could rapidly progress lead candidates through pre-clinical testing and into first in man studies. I have always found Onyx Scientific to be very customer focused, flexible and responsive.
The team at Onyx Scientific definitely provide value for money. They meet deadlines, making them a safe pair of hands and more cost effective in the long run than potentially cheaper competitors.
Over the ten years we have worked with Onyx Scientific, they have continuously expanded their services and kept up to date with the demands of the industry. As such, Onyx Scientific now provides an end to end chemistry solution and continues to deliver an outstanding service.
Onyx Scientific has a tremendous reputation as a premier CDMO, and the results the team achieves consistently exceed our highest expectations. If you’re scaling drug substances to take into GMP manufacture, look no further than Onyx Scientific.