Onyx is now licensed to manufacture commercial API from our UK facility

Experts in small molecule API development & manufacturing

Flexible and responsive to each client’s specific requirements

Integrated approach for maximising efficiency and value

At Onyx we are proud of our reputation for providing quality services, with solutions specific to each client’s individual needs.

Testimonials

  • “I have worked with Onyx for over 14 years on projects spanning the pre-clinical phase through to process validation. They continue to deliver pragmatic, cost-effective solutions for my clients when faced with the inevitable technical challenges that they will encounter on these projects. Highly recommended and a great CDMO to work with.”

    Ron Lawrence, Managing Partner Cerebro CMC
  • “We recently selected Onyx Scientific to work on two projects, both ligands for inclusion in nanomedicine drug substances. One project is essentially complete, and the other about 50% of the way through as of Q2 2024. Onyx have been very professional and easy to deal with throughout. Their team has demonstrated great expertise, were very approachable and demonstrated a great understanding of our requirements. The quotes provided were honest and detailed, with a clear breakdown of costs and no hidden fees, and during the project the communication has been transparent and regular. Their chemistry, process, and analytical team have been first class, instilling confidence in their ability to deliver on time and to a high standard. Overall, it has been a pleasure to work with Onyx.”

    Stewart Bartlett, CEO at Ferronova
  • “NRG Therapeutics initially contracted work with Onyx for a 500g non GLP scale-up of our lead molecule. The high quality of the delivery, the rapid turn-around, the seamless communication, and the clarity of the weekly reports comforted us in our choice. We have since contracted more work with Onyx including additional scale-up, route optimisation, salt and polymorph screening. All have been conducted with the same high standard of quality showcasing their problem-solving skills and making Onyx one of NRG therapeutic’s trusted partners.”

    Gilles Ouvry, VP, NRG Therapeutics
  • “We recently started working with Onyx Scientific on the development of our lead compound, an oral small molecule therapy for the rare disease PKU. From the start, we had seamless access to Onyx’s technical team, who were not only highly knowledgeable but also incredibly approachable and demonstrated excellent understanding of our requirements. The transparency of the quote provided was refreshing, with a clear breakdown of costs and no hidden fees. The quality of their proposal was impressive and tailored specifically to our needs. Moreover, Onyx demonstrated good capacity to handle our project, instilling confidence in their ability to deliver on time and to a high standard. Overall, the onboarding process was smooth, professional, and left us excited to work with Onyx.”

    Willem van Weperen, CEO, Pluvia Biotech
  • “Starting with a typical medicinal chemistry technical package, we have so far performed three API campaigns at Onyx including two GMP. I have been impressed by their ability to combine all the muti-disciplinary aspects of API small scale GMP production in a very pragmatic and efficient approach. What differentiates Onyx from other CDMOs on similar scale, is an impressive know-how in designing crystallisations, incorporating them in a very efficient process and delivering high purity batches.”

    Alain Priour, CMC Project Leader at Domain Therapeutics

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Knowledge hub

Here at Onyx our experts are committed to bringing you their latest insights from the API development and manufacturing world. In our knowledge hub you can find an array of content curated to help you overcome challenges and achieve success.

News

Onyx Scientific Aims for European Growth with New BD Hire

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Insights

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Explore Our Facility

Onyx’s virtual site tour explores our facility in Sunderland, UK and allows users to navigate through the laboratories where our team manages preclinical research and development, analytical method development, solid state chemistry and GMP/non GMP API scale up capabilities. For those unable to visit our team and facility in person, this virtual tour allows you to view some of our equipment, see some of our team members in action and watch videos of some of our processes and equipment.