Onyx is now licensed to manufacture commercial API from our UK facility

Large Scale Chemist


📍 Onyx Scientific | Pharmaceutical CDMO | Location: Sunderland |Full-time | Permanent

Are you a chemist looking for a hands-on role where you can apply your technical expertise in a GMP-regulated environment and make a tangible impact?

At Onyx Scientific, we partner with academic, biotech, and pharmaceutical organisations worldwide, providing high-quality scientific support from early discovery through to commercial manufacture.

Due to continued growth, we’re looking for a GMP Chemist to join our manufacturing and scale-up teams.

The Role

As a Large Scale Chemist, you will play a central role in scale-up activities, operating reactors in the 50L–100L range while working in line with company safety standards and SOPs. You will support the delivery of reliable, high-quality outputs and collaborate closely with colleagues across the business.

This is a rewarding opportunity to work on complex pharmaceutical manufacturing projects while developing your experience within a successful and growing pharmaceutical organisation.

Key Responsibilities
  • Perform kilo-scale chemistry with minimal supervision
  • Operate large-scale reactor processes safely and effectively
  • Maintain a high standard of cleanliness and housekeeping
  • Write weekly reports with support and guidance
  • Review completed documentation for accuracy and compliance
  • Identify and report issues relating to paperwork or documentation
  • Comply fully with company SOPs and training requirements
  • Communicate delays, challenges, or issues clearly and constructively
About You

We’re looking for an enthusiastic and detail-oriented chemist who enjoys practical laboratory and manufacturing work within a structured, regulated environment.

You’ll be committed to working safely, maintaining high-quality standards, and ensuring documentation is completed accurately and on time. You’ll be comfortable working both independently and collaboratively while contributing positively to team objectives.

Essential Skills and Experience
  • Degree in Chemistry or a related scientific discipline.
  • Strong understanding of chemical techniques and laboratory practices.
  • Experience working safely in laboratory or manufacturing environments.
  • Excellent attention to detail, particularly relating to documentation and compliance.
  • Strong organisational and time-management skills.
  • Effective communication and interpersonal skills.
  • Commitment to Health, Safety and Environmental requirements.
  • Ability to follow procedures accurately and work within regulated systems.
Desirable Experience
  • Experience of kilo-scale or large-scale chemical processing
  • Exposure to GMP-regulated environments
  • Experience working within manufacturing, scale-up, or pilot plant operations
  • Experience with advanced chemical processes such as gas reactions or air-sensitive chemistry
  • Familiarity with SOP-driven quality systems and documentation requirements
What You’ll Bring
  • A proactive and self-motivated approach
  • Strong organisational and prioritisation skills
  • Exceptional attention to detail
  • Problem-solving ability and a continuous improvement mindset
  • Flexibility and adaptability to meet operational requirements
  • A collaborative attitude and willingness to support colleagues across teams
  • A positive and enthusiastic approach to contributing to team success
What We Offer

🧪 The opportunity to work on meaningful manufacturing and scale-up projects

🤝 A supportive and collaborative scientific environment

📈 Career development within a growing pharmaceutical CDMO

Benefits

Company events

🚲 Cycle to work scheme

🧠 Health & wellbeing programme

🛡 Life insurance

🏥 Private medical insurance

🚗 Free on-site parking

👉 If you’re passionate about chemistry and keen to make a meaningful contribution within a collaborative GMP manufacturing environment, we’d love to hear from you.

Apply today to join the Onyx Scientific team.

Apply for the position of Large Scale Chemist